Monitor biomass and growth rates in your bioreactors with high-resolution growth curves using the CGQ BioR. Optical biomass measurements are based on scattered light detection without the use of integrated sensors. Simply mount the sensor plate to the outside of your reactor and monitor the biomass through the vessel wall. Follow the growth of your cultures in real time to gain actionable insights into your strain’s growth behavior.
Using an array of LEDs and photodiodes, the sensor emits light through the wall of the vessel and measures the amount of light that is scattered back. The more cells that are in the reactor, the more light that is scattered back. This backscatter signal can be correlated with offline cell density data, such as OD600 or cell dry weight (CDW).
The sensor of the CGQ BioR contains two LEDs and a photodiode detector. The two LEDs with different wavelengths are used to allow for precise measurements at low and high cell densities.
Light is emitted from the LEDs into the culture medium. While most photons go straight through the broth, some are scattered by the cells and return to the photodiode, which measures the scattered light intensity. The higher the cell density, the more light is scattered back to the photodiode.
Each sensor is positioned outside of the bioreactor, measuring the biomass through the vessel wall.
Several sensors can be connected to a single base station. The base station bundles the data from all monitored flasks and sends it to the software.
The software then analyzes the biomass signals and presents it as a real-time growth curve. Datasets can be easily exported for further data analysis.
The CGQ BioR is compatible with a variety of bioreactors. Different sized attachment straps provide maximum flexibility, allowing the same sensor to be used with different bioreactor sizes and manufacturers.
For different reactor types:
For different reactor sizes:
Manual sampling-based data is often not sufficient to fully understand the bioprocess. Offline sampling is complex and time consuming, resulting in lower measurement frequency with most pulls being at the start or the end of the experiment. This means that critical information from your growth phases are being overlooked, and could have a detrimental impact on your final product. Automated online measurements, on the other hand, never miss a moment. With a high resolution growth curve, you can detect bioprocess changes in real time.
If you have an account with us please log in.
Cookie | Duration | Description |
---|---|---|
cookielawinfo-checkbox-analytics | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Analytics". |
cookielawinfo-checkbox-functional | 11 months | The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". |
cookielawinfo-checkbox-necessary | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookies is used to store the user consent for the cookies in the category "Necessary". |
cookielawinfo-checkbox-others | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Other. |
cookielawinfo-checkbox-performance | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Performance". |
viewed_cookie_policy | 11 months | The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. It does not store any personal data. |