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Overview

As the central piece of sbi’s DOTS Platform, the MPS enables effortless online monitoring of multiple parameters in shake flasks. From dissolved oxygen (DO) and biomass monitoring to fluorescence detection – the MPS turns the standard shake flask into smart bioreactors.

  • Advanced data and control capabilities: The MPS turns your shake flasks into low-cost and high-throughput bioreactors
  • Say goodbye to manual sampling and save time with automated, online monitoring of many shake flasks in parallel
  • Select parameters that are critical to your process
    • Dissolved oxygen, Biomass, Fluorescence, and more!
  • Powerful DOTS Software for easy sensor handling and real-time data visualization

How It Works

Our Multiparameter Sensor (MPS) enables dissolved oxygen, backscatter (biomass), and fluorescence monitoring in shake flasks. The platform-type sensor is built to accommodate additional sensor parameters as they are developed by the sbi team, ensuring scientists will have the latest technology.multiparameter-sensor-for-shake-flasks-sbi

 

Customize Your Smart Shake Flask

Choose from an array of parameter-specific sensor-and-software modules to build the smart shake flask that meets your needs. With the MPS, you can continue to expand your shake flask sensing capabilities as new sensors are added in the future.

Biomass

MPS

Monitor biomass and growth rates non-invasively through the vessel wall via backscattered light detection. The real-time, high-resolution growth curves provide actionable insights into your strain's growth behavior.

Dissolved Oxygen

SensorPills

When combined with the single-use Dissolved Oxygen Sensor Pill, the MPS continuously detects changes in the DO level of your culture. 

Fluorescence

Fluorescence

An integrated spectrophotometer enables fluorescence monitoring of various wavelengths, also in parallel, and evaluation of fluorescent protein expression.

Parameter-Based Feeding

LIS

Integrate the MPS with sbi's Liquid Injection System (LIS) to precisely feed liquids based on specified parameters (i.e. DO, biomass). These advanced control options elevate your shake flask experiments to a new level of precision and effectiveness.

Environmental Parameters

Environmental

Embedded ambient sensors in the MPS enable the measurement of environmental parameters such as temperature, shaking speed, and humidity, providing comprehensive insights into your bioprocess and indicating shaker openings or other disruptions. 

Do you want bioreactor-like capabilities on the shake flask level?

EXPLORE THE DOTS PLATFORM

Hardware & Software Components

Multiparameter Sensor & Adapter

multiparameter-sensor-adapter-icon (2)

Each sensor plate is positioned in the adapter under the cultivation vessel and measures non-invasively through the vessel wall.

USB Hub

usb hub in grey circle

Several sensor plates can be connected to a single hub. The hub bundles the data from all monitored flasks and sends it to the DOTS Software.

DOTS Software

SBI-Icon-dots-software-computer-2

The DOTS Software receives the data from the hub and visualizes relevant parameter data in real-time.

What Our Customers Are Saying

"You don't get more product by trying to get more product, but by gaining more insights into your process."

-Raul Reveles (Senior Bioprocessing Engineer, Bond Pet Foods)
Bond Pet Foods Logo white

Specifications

Compatible Laboratory Infrastructure

The MPS is compatible with a variety of shake flasks. The adapter system provides maximum flexibility, allowing the same sensor plate to be used with different shake flask sizes.

  • Any shake flask size ranging from 100 mL to 2000 mL

  • Glass and single-use flasks

Compatibility

Compatible Laboratory Infrastructure

The MPS is compatible with a variety of shake flasks. The adapter system provides maximum flexibility, allowing the same sensor plate to be used with different shake flask sizes.

  • Any shake flask size ranging from 100 mL to 2000 mL

  • Glass and single-use flasks

Downloads

From Estimation To High-Resolution Growth Curves

Why CGQ for your Shake Flasks?

Manual sampling-based data is often not sufficient to fully understand the bioprocess. Offline sampling is complex and time consuming, resulting in lower measurement frequency with most pulls being at the start or the end of the experiment. This means that critical information from your growth phases are being overlooked, and could have a detrimental impact on your final product. Automated online measurements, on the other hand, never miss a moment. With a high resolution growth curve, you can detect bioprocess changes in real-time.

Cell Growth Quantifier (CGQ)
Success Growth Graph

Customer Success Stories

SBI-Success-Table-2
"Our group has been using the Cell Growth Quantifier (CGQ) for roughly five years by now and even though we often use the device for screenings, it also is the perfect tool for toxicity tests.”

-Dr. Julia Hitschler (University of Frankfurt)
Goethe University Frankfurt
Cell Growth Quantifier (CGQ)
"The backscatter data we gathered here with the CGQ system clearly shows a match with another growth characterisation parameter, in this case with the oxygen transfer rate (OTR)."

-Frédéric Lapierre (HS München)
HM

Want To Connect The DOTS In Your Bioprocessing?